TNF and psoriasis: Human STK40 was reported to inhibit TNF-α-induced NF-κB activation.18 In the mouse psoriasis model, miR-31 increases the basal level and TNF-α-induced cytokine and chemokine production via targeting Stk40.35 This mechanism is also conserved in the endothelial–mesenchymal transition and in associated secretory phenotype induced by TGF-β.