After observing the reduction in BRCA1 expression, a reduction in DNA DSB repair capacity and increased chromatid damage with TTFields exposure, the radioresponse of our panel of NSCLC cell lines was determined via clonogenic cell survival after the cells received either 2 or 4 Gy IR followed by TTFields treatment for 24, 48 and 72 h. Here, BRCA1 is linked to non-small cell lung carcinoma.