“This work was supported by National of Institute of Neurological Disorders and Stroke grant R21NS077177 and by Texas A&M Health Science Center funds to M.R. We thank N. Yumoto for AChR antibodies, J. Lawler for SOD2 antibodies, J. Samuel for access to a confocal microscope and R. Miranda for access to a real-time PCR machine. The gene discussed is SOD2; the disease is Stroke.