IL1B and infection: Mice were subjected to dentoalveolar infection with a mixture of four common human endodontic pathogens, and were treated subcutaneously with neutralizing antibodies against mouse IL-1α, IL-1β, or both (anti-IL-1α/β) on days 0, 3, 6, 9 and 12 relative to infection, or received unreactive goat IgG as a control.