As shown in Table 1, the expression of LIMK1 and destrin was related to the pathological degree of differentiation (P = 0.001, P = 0.022), tumor size (P = 0.001, P = 0.004), clinical stage (P = 0.002, P = 0.007), and metastasis (P < 0.001, P = 0.009) in colon cancer, but not to gender and age. The gene discussed is LIMK1; the disease is neoplasm.