In thelast few years, a decisive role of FBP1-repression in the initiation of severaltumour types has been described; metabolically, the loss of FBP1 increasedglycolytic flux, and decreased respiration 6, 7, 8; morphologically, FBP1-loss has been demonstrated to be essential forthe epithelial to mesenchymal transition (EMT), an essential morphologicalreprogramming step of epithelial tumor cells required for the dissemination of tumorcells from primary tumors, subsequently leading to the formation of metastasis 7. Here, FBP1 is linked to neoplasm.