CD4 and viral infectious disease: Usually no symptoms are shown during that phase makinginfected people unaware of their status 145.Despite the term "latency", the viral infection is far from latent, withlarge numbers of CD4+ T cells becoming infected and dying every day.Finally, the number of CD4+ T cells declines to the point (around 200cells/mL) at which immune control of adventitious infectious agents can no longer bemaintained, and opportunistic infections begin to appear 145.