Asgonococci bind to human CR3 (hCR3) integrin to invade cervical cells and thathuman factor H bridges the interaction between the bacteria and hCR3, thenfuture transgenic mouse models, expressing both hCR3 and human factor H, mayfurther mimic a bona fide gonococcal infection in vivo. The gene discussed is CFH; the disease is bacterial sexually transmitted disease.