These were the Dyn1 mutationsR256L (Vps1-R298L) causing exercise-induced collapse in Labradors, A408T(Vps1-A447T) that causes epilepsy in the fitful mouse model, and the Dyn2mutation G358R (Vps1-G397R) which causes CMT disorder 19, 20, 29. The gene discussed is DNM1L; the disease is epilepsy.