Case 1 defined with G6PD deficiency had a relatively long duration of illness compared to G6PD normal cases, but relatively low total parasite burden (judged by plasma PfHRP2), likely reflecting overall low parasite multiplication rate, consistent with the possibly reduced falciparum parasite invasion [47] and growth [48] of G6PD deficient red cells observed in vitro. Here, G6PD is linked to hyperinsulinemic hypoglycemia, familial, 4.