CXCL5 and neoplasm: By counterstaining the fibroblasts, we further found that, although CXCL5 staining was observed in the tumor mesenchyme, CXCL5 was primarily expressed in the tumor lesions rather than the fibroblasts, which were visualized with the fibroblast marker α-smooth muscle actin (αSMA) (Fig. 3a and b).