CXCR4 expression has also been linked to over 20 different types of cancer like breast cancer [10], colon cancer [11], prostate cancer [12] and melanoma [13] demonstrating that the CXCR4/CXCL12-axis is involved in tumor progression, angiogenesis, metastasis and survival. This evidence concerns the gene CXCR4 and Familial prostate cancer.