We focused on proteins that were either co-enriched with ATP7A to a similar extent as the bait (fold of enrichment log2 >6), were present in the BCS and copper treated ATP7A interactomes (Figure 2C), were associated with or causative of neurodegeneration (VAC14, strumpellin, NFKB1, and GIGYF2/PARK11) as well as mental disorders (NSF, DOCK7, GIGYF2, and COG complex subunits, Figure 3), and/or were present in compartments where ATP7A traffics to and from. This evidence concerns the gene NFKB1 and mental disorder.