The serum levels of TP53 in HCC and T2DM patients were higher and had no correlation with CXCL1, interleukin-2 receptor-alpha (IL-2R alpha), PECAM-1, and prolactin, whereas there was an important correlation between tumor protein p53(TP53) and CXCL12 in HCC and in T2D-HCC patients [73]. This evidence concerns the gene CXCL1 and type 2 diabetes mellitus.