In our present study, CRP, which is a marker of pleiotropic effects of statins, were significantly lower in those with hypercholesterolemia than those without (1.52 ± 3.72 vs. 2.23 ± 4.40 mg/dL, P = 0.024) among 746 patients whose serum CRP levels were measured on admission. The gene discussed is CRP; the disease is Hypercholesterolemia.