In our study on hypertensive patients of Kashmir, we found that among 52 hypertensive cases the frequency of ACE DD genotype to be 46.15% (24/52), II 23.07% (12/52) and DI 30.77% (16/52) however no statistical significance was observed between the ACE gene I/D polymorphism and hypertension. The gene discussed is ACE; the disease is Hypertension.