In 30–50% of cases DCM is linked to familial etiology, including mutations in the regulatory thick and thin myofilament proteins - myosin, actin, the Troponin (Tn) complex, Tropomyosin (Tm), and Titin (Ttn) (Kärkkäinen and Peuhkurinen, 2007; Lu et al., 2013). This evidence concerns the gene TTN and familial dilated cardiomyopathy.