The results of the present study indicated that the levels of MCP-1 and CCR2 were similar in the Western blot analysis, and the counts of MCP-1 and CCR2 immunoreactive cells in the hippocampus were also similar among the normal, KA, sham, auricular, and Zusanli groups at 6 weeks after KA-induced epileptic seizures. The gene discussed is CCR2; the disease is Seizure.