ITGAM and cancer: After co-staining of CD11b+F4/80+ macrophages with additional markers Ly6c and Gr1, we found an almost 30% elevation of CD11b+F4/80+Gr1+ cells (p≤0.05), which corresponds to inflammatory monocytes but may also include phenotypic MDSC (myeloid-derived suppressor cells) (Fig. 5B) often associated with chronic inflammation or cancer [45].