HCST and neoplasm: In addition, high levels of HCST [59, 60], C3AR1 [61], GBP4 [62], LY96 [63], ANKRD22 [64], FPR3 [65] and FCGR2A [66], have also been related to immune activation and/or inflammatory response in tumours; however, their role in basal-like breast malignancies are yet to be uncovered.