As Fig 3 revealing, the sub-network among 7 DEmRNAs which were our concerns and DEmiRNAs in READ deciphered that LONRF2 was negatively regulated by hsa-mir-335, hsa-mir-20a and hsa-mir-452; has-mir-182 negatively correlated with PDZRN4, GNAO1 and CNGA3; and hsa-mir-19b-2 negatively regulated GNAO1 and CNGA3. The gene discussed is GNAO1; the disease is reading.