A systematic review and meta-analysis of twenty prospective studies reported that NAFLD was associated with an increased risk of incident T2DM with a pooled relative risk of 1.97 for alanine aminotransferase, 1.58 for aspartate aminotransferase, and 1.86 for ultrasonography, respectively [7]. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.