A total of 10 independent associated SNPs (log10BF>5) were prioritized for replication (Supplementary Table S5; Supplementary Figure S4); of these, three were in or near GPHN, two represent previously reported associations in CONVERGE that did not replicate in PGC6 and one was the strongest reported association in the original PGC study.22 No single SNP in either the females-only or recurrent MDD analyses attained genome-wide significance (Supplementary Figure S3). Here, GPHN is linked to major depressive disorder.