Treatment of human gastric carcinoma SGC-7901 cells with vitamin E succinate (RRR-α-tocopheryl succinate) led to a decreased nuclear and cytosolic RelA protein amount, diminished NF-κB-DNA binding, decrease in protein expression of Bcl-2, increased protein levels of Bax, and cleaved caspase-9, caspase-3 and PARP. This evidence concerns the gene NFKB1 and gastric carcinoma.