IL1B and neoplasm: The NF-κB-driven gene products include cytokines/chemokines IL-1, IL-8, TNF, IL-6, MCP-1, pro- and anti-apoptotic factors cIAPs, c-FLIP, A20, Bcl-XL, angiogenesis regulator vascular endothelial growth factor (VEGF), matrix metalloproteinases (MMP)-2, MMP-9 in non-transformed or tumor cells in response to a variety of stimuli, including growth factors, cytokines, hormones, microbial and chemical compounds [10].