The single sCJD case with CAA had the APOE-ɛ3/4 genotype, while the two vCJD cases with diffuse Aβ parenchymal deposits comprised one case with the APOE-ɛ3/4 genotype and one case with the APOE-ɛ2/3 genotype. This evidence concerns the gene APOE and variant Creutzfeldt-Jakob disease.