While the parenchymal Aβ deposits in the brains of the hGH recipients show similarities to the deposits found in Alzheimer’s disease, the distribution of the Aβ pathology does not appear to resemble the pattern that is characteristic of Alzheimer’s disease, but shows a distribution more similar to that previously described in hDM-iCJD [36]. The gene discussed is GH1; the disease is Alzheimer disease.