TNFSF10 and cancer: As shown in Figure 4, delivery of GFP‐TRAIL was very effective in killing cells in certain cancer cell lines evaluated, particularly small‐cell lung cancer line H446 and pancreatic cancer line BxPC‐3, with 68 ± 2% and 64 ± 3% cell death, respectively, when transfected with PBAE 447/TRAIL‐DNA (Table 3).