As shown in Figure 9, p-Akt was significantly increased after MI compared to that in the sham group, and PR39-ADM significantly increased p-Akt levels compared to that in the AAV-null (P < 0.05) and NS groups (P < 0.05); however, there was no significant difference between AAV-null and NS groups. The gene discussed is AKT1; the disease is myocardial infarction.