These include ADA, AK1, ENTPD1, NME1, NME3, NME4, NME6, PNP, and PRUNE. However, only three genes, ENTPD2, NME3, and PRUNE, are significantly upregulated in rpDLB when compared with DLB. This evidence concerns the gene NME3 and Lewy body dementia.