These include ADA, AK1, ENTPD1, NME1, NME3, NME4, NME6, PNP, and PRUNE. However, only three genes, ENTPD2, NME3, and PRUNE, are significantly upregulated in rpDLB when compared with DLB. The gene discussed is ENTPD2; the disease is Lewy body dementia.