MACC1 and hepatocellular carcinoma: Metastasis-associated in colon cancer 1 (MACC1) was overexpressed in many tumors, including colon cancer (Arlt and Stein, 2009), human lung cancer (Shimokawa et al., 2011), hepatocellular carcinoma (Sun et al., 2015) and human malignant glioma (Yang et al., 2014).