This prediction was recently experimentally confirmed across a plethora of experimental assays and disease conditions including EC monolayers and embryoid-body sprouting assays exposed to high VEGF-A (electronic supplementary material, figure S2), intraocular injection of VEGF-A in the mouse retina (figure 5b), the oxygen induced retinopathy (OIR) model of ischaemia driven ocular neovascularization, and finally syngenic mouse glioblastoma tumours [35]. The gene discussed is VEGFA; the disease is glioblastoma.