When compared with our group’s previous study that examined urinary peptidomics in women with preeclampsia, we found the ortholog peptides of Umod upregulated in preeclampsia.22 In another independent study by Kononikhin et al23 that examined the urinary peptidome in mild and severe preeclampsia, the same sequence of peptides of Umod was identified as early predictors of preeclampsia (Figure 4A). The gene discussed is UMOD; the disease is preeclampsia.