A previous biopsy had suggested possible squamous cell carcinoma, but the morphology and IHC profile with >90% of the cells positive for p40, S100 and smooth muscle-specific actin (CK5 was positive in about 40% of the cells) was consistent with epithelial-myoepithelial carcinoma. The gene discussed is KRT5; the disease is epithelial-myoepithelial carcinoma.