Clinico-radiologically metastasis of rectal cancer was suggested, but considering the IHC profile, a separate lung cancer with liver metastasis was proposed by the pathologist, especially since TTF-1 (clone 8G7G3/1) was positive in the lung and liver tumours, although the CK7/CK20 profile was the same in the rectal cancer. The gene discussed is KRT7; the disease is lung carcinoma.