LGR5 and hydrops fetalis: Moreover, we found that the progeny of Lgr5+ cells (mT−/mG+) were detected in over 40% of neogenic HFs in the wound (Fig. 5o,p), and the number of Lgr5+ cell progeny in individual neogenic HFs differed greatly and ranged from <3% to over 90% of total HF cells (Fig. 5p).