CEACAM5 and cancer: 1983). The introduction of rats to specific cancer-causing agents, for example, DEN, has been found to bring about rise in coursing AFP levels (Becker & Sell 1979). Carcinoembryonic antigen (CEA) is a member of the immunoglobulin supergene family and a 180–200 kDa highly glycosylated protein that is utilized clinically as a tumour marker for diagnosing the recurrence of numerous sorts of cancers (Zimmer & Thomas 2001).