Defects in the N-linked glycosylation genes ALG3, ALG8, and ALG9, as well as the O-linked glycosylation gene B3GALTL, variably result in polycystic kidneys, cleft lip or palate, polycystic ovaries, and abnormal development of the brain including the corpus callosum [44–47]. This evidence concerns the gene ALG9 and polycystic ovary syndrome.