NRXN3 and fragile X syndrome: For this analysis, one subject with Fragile X syndrome was excluded but three subjects with clinically significant CNVs (A2BP1/RBFOX1 deletion [62] (1.0 < WB5HT-z < 1.75), maternal interstitial duplication 15q11-q13 (Normal-5HT group), and NRXN3 deletion (Normal-5HT group)) were included.