An magnetic resonance imaging (MRI) of her pelvis showed a solitary tumor, and subsequent CT of her thorax and abdomen, mammography, and endoscopy could not reveal or indicate the primary location of the tumor; in addition, the tumor markers we use in our screening were all within normal range: carcinoembryonic antigen (CEA), CA125, CA15-3, CA19-9, neuron-specific enolase (NSE), and chromogranin A (CgA). This evidence concerns the gene ENO2 and neoplasm.