FOXP3 and neoplasm: Another group of studies negates its value (Chaput et al. 2009; Loddenkemper et al. 2006), whereas Kim et al. (2013) are of the opinion that it is high expression of FoxP3+ in tumor cells and not in Treg lymphocytes that is related to a bad prognosis as compared to patients with low FoxP3+ expression.