Both CBTAU-7.1 and CBTAU-22.1 also show immunoreactivity of pathological tau structures in primary age-related tauopathy (PART) [13], progressive supranuclear palsy (PSP), frontotemporal dementia with microtubule-associated tau gene mutation (FTDP-17) and Pick’s disease cases, indicating that the phospho-epitopes detected by CBTAU-7.1 and CBTAU-22.1 are present throughout different tauopathies (Fig. S9). Here, MAPT is linked to tauopathy.