To explore the role of increased Fstl1 in silica-induced lung fibrosis, C57BL/6J mice were intraperitoneally injected with FSTL1 neutralizing antibody (22B6 mAb)24 every other day from day 1 to 19 after silica treatment (Fig. 6a). Here, FSTL1 is linked to pulmonary fibrosis.