Mutations and overexpression of the neuroblastoma RAS viral (v‐ras) oncogene homolog (NRAS) are found across multiple tumor types and are common in highly metastatic cancers such as tumors of unknown primary, melanomas, and sarcomas that display a striking propensity for lung metastasis (Disibio & French, 2008; Stephen et al, 2014; Forbes et al, 2015). The gene discussed is NRAS; the disease is melanoma.