NRAS and cancer: A link between NRAS gain and lung metastasis is plausible, since both occur across human cancer types (Forbes et al, 2015), NRAS mutations/gain occurs prior to the onset of metastasis in melanoma (Edlundh‐Rose et al, 2006; Colombino et al, 2012), and since NRAS mutations/gain is especially frequent in cancers that commonly home to the lungs (i.e. melanoma, thyroid and colon adenocarcinomas, acute myeloid leukemia, and metastatic tumors of unknown primary).