The age of onset of hearing loss, which ranges from the first to the fifth decade of life, differs among those with different mutations in KCNQ4. The age of onset of hearing loss caused by p.Q71fs in the N-terminal, p.G285C in the pore region, and p.A349Pfs in S6trans is in the first decade of life [15, 23, 25]. The gene discussed is KCNQ4; the disease is hearing loss disorder.