In MKN28 and MKN45 human gastric epithelial cells, transfected CagA deregulated β-catenin and then transactivated T-cell factor/lymphoid enhancer factor (TCF/LEF) and CDX1 transcription factor to induce the expression of cancer-associated Wnt target genes, such as c-myc and cyclin d1 [108]. Here, S100A8 is linked to cancer.