FOLH1 and neoplasm: The PSMA+ PC3 PIP-to-PSMA− PC3 flu tumor ratios were 110 ± 22 at 1 h, 232 ± 26 at 2 h, and 182 ± 15 at 3 h p.i. Renal uptake for 68Ga-43 was highest at 1 h, 106 ± 23 % IA/g, much higher than that seen for the DOTA-conjugated radioligand 68Ga-42 (26.5 ± 6.9 % IA/g), and showed faster renal clearance, which decreased to 34.7 ± 5.7 % IA/g by 2 h p.i. There was no significant difference in PSMA+ PIP tumor uptake between 68Ga-42 and 68Ga-PSMA-11 or between 68Ga-43 and 68Ga-PSMA-11 (p > 0.05) at any time-point.