KLK3 and metastatic neoplasm: There were 5/155 (3%) men in Group-B who were diagnosed with metastatic CaP prior to age 55, which coincided with their first PSA test 130/155 (84%) patients were included in group C, of which 8/130 (6%) patients underwent screening prior to initial diagnosis of CaP and 122/130 (94%) had their first PSA test at the time of diagnosis with metastatic disease Table-3.