However, the heterogeneity analysis showed that there was a relatively high-level heterogeneity in our meta-analysis of HIV/AID patients (Q = 401.6, I2 = 90.3%, p = 0.000) and cancer individuals (Q = 76.4, I2 = 63.4%, p = 0.000), and no heterogeneity was found in transplant recipients (Q = 8.0, I2 = 37.3%, p = 0.157). The gene discussed is AICDA; the disease is cancer.