VEGF and bFGF are regarded as most potent mediators of angiogenesis (Folkman, 2002[6]; Gupta and Qin, 2003[10]), and VEGF appears to play a dormant role in different cancers, including cancers of colon and lung (Frandsen et al., 2016[7]). Here, FGF2 is linked to malignant colon neoplasm.