This effect, nevertheless, may be indicative of a cardioprotective influence of the extract, since exenatide, an incretin mimetic drug, used to improve normal glucose metabolic function in T2DM patients through its agonist effects on the glucagon-like peptide-1 receptor, is observed to elevate heart rate in human T2DM patients [23]. This evidence concerns the gene GLP1R and type 2 diabetes mellitus.