MTOR and laryngeal carcinoma: However, to the best of our knowledge, PPD has not been tested in laryngeal carcinoma Hep-2 cells and there are still many issues to be resolved: (1) the anticancer effect of PPD and its molecular mechanism in laryngeal carcinoma Hep-2 cells; (2) how PPD affects the localization and expression levels of signal molecules in mTOR pathways; (3) whether there is an intimate relationship between PPD anticancer function and the distribution features of mTOR and its downstream targets.