In recent studies, FPR1 has been associated with anti-bacterial inflammation and metastasis of malignant glioma cells, while FPR2 is implicated in the pathogenesis of chronic inflammatory diseases such as systemic amyloidosis, Alzheimer’s disease, atherosclerosis, systemic lupus erythematosus and ovarian cancer metastasis et al. [15,16,17,18,19]. Here, FPR2 is linked to early-onset autosomal dominant Alzheimer disease.